MED27-TG Gene Fusion FISH Probe
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Catalog: |
GFFP-MED27/TG-07052 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MED27-TG Gene Fusion FISH Probecan detect the fusion of MED27 and TG genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MED27-TG Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Thyroglobulin |
Gene Summary 1 |
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8q24.22 |
Coordinates 1 |
This gene maps to 133879204-134147143 in GRCh37 coordinates. |
Gene Name 2 |
Mediator Complex Subunit 27 |
Gene Summary 2 |
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9q34.13 |
Coordinates 2 |
This gene maps to 134735498-134955253 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MED27/TG-07052-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MED27/TG-07052-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MED27/TG-07052-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MED27/TG-07052-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MED27/TG-07052-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MED27/TG-07052-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MED27/TG-07052-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MED27/TG-07052-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MED27/TG-07052-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MED27/TG-07052-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MED27/TG-07052-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MED27/TG-07052-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MED27/TG-07052-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MED27/TG-07052-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MED27/TG-07052-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MED27/TG-07052-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MED27/TG-07052-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MED27/TG-07052-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MED27/TG-07052-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MED27/TG-07052-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MED27/TG-07052-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MED27/TG-07052-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MED27/TG-07052-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MED27/TG-07052-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MED27/TG-07052-AQAQ |
467nm;467nm |
418nm;418nm |
|
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