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MECP2-F8 Gene Fusion FISH Probe

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Catalog: GFFP-MECP2/F8-07091
Classification: Gene Fusion FISH Probes
Description: The MECP2-F8 Gene Fusion FISH Probecan detect the fusion of MECP2 and F8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MECP2-F8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Coagulation Factor VIII
Gene Summary 1 This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome X
Locus 1 Xq28
Coordinates 1 This gene maps to 154064063-154250998 in GRCh37 coordinates.
Gene Name 2 Methyl-CpG Binding Protein 2
Gene Summary 2 DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of cognitive disability in females. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
Chromosome 2 ChromosomeX
Locus 2 Xq28
Coordinates 2 This gene maps to 153287263-153363188 in GRCh37 coordinates.
Associated Diseases Liver Hepatocellular Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MECP2/F8-07091-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MECP2/F8-07091-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MECP2/F8-07091-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MECP2/F8-07091-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MECP2/F8-07091-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MECP2/F8-07091-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MECP2/F8-07091-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MECP2/F8-07091-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MECP2/F8-07091-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MECP2/F8-07091-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MECP2/F8-07091-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MECP2/F8-07091-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MECP2/F8-07091-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MECP2/F8-07091-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MECP2/F8-07091-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MECP2/F8-07091-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MECP2/F8-07091-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MECP2/F8-07091-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MECP2/F8-07091-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MECP2/F8-07091-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MECP2/F8-07091-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MECP2/F8-07091-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MECP2/F8-07091-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MECP2/F8-07091-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MECP2/F8-07091-AQAQ 467nm;467nm 418nm;418nm

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