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MDM2-DIP2B Gene Fusion FISH Probe

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Catalog: GFFP-MDM2/DIP2B-07124
Classification: Gene Fusion FISH Probes
Description: The MDM2-DIP2B Gene Fusion FISH Probecan detect the fusion of MDM2 and DIP2B genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MDM2-DIP2B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 MDM2 Proto-oncogene
Gene Summary 1 This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Chromosome 1 Chromosome 12
Locus 1 12q15
Coordinates 1 This gene maps to 69201970-69239212 in GRCh37 coordinates.
Gene Name 2 Disco Interacting Protein 2 Homolog B
Gene Summary 2 This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
Chromosome 2 Chromosome12
Locus 2 12q13.12
Coordinates 2 This gene maps to 50898767-51142450 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MDM2/DIP2B-07124-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MDM2/DIP2B-07124-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MDM2/DIP2B-07124-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MDM2/DIP2B-07124-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MDM2/DIP2B-07124-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MDM2/DIP2B-07124-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MDM2/DIP2B-07124-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MDM2/DIP2B-07124-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MDM2/DIP2B-07124-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MDM2/DIP2B-07124-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MDM2/DIP2B-07124-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MDM2/DIP2B-07124-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MDM2/DIP2B-07124-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MDM2/DIP2B-07124-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MDM2/DIP2B-07124-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MDM2/DIP2B-07124-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MDM2/DIP2B-07124-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MDM2/DIP2B-07124-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MDM2/DIP2B-07124-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MDM2/DIP2B-07124-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MDM2/DIP2B-07124-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MDM2/DIP2B-07124-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MDM2/DIP2B-07124-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MDM2/DIP2B-07124-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MDM2/DIP2B-07124-AQAQ 467nm;467nm 418nm;418nm

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