MBNL2-GLI3 Gene Fusion FISH Probe
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Catalog: |
GFFP-MBNL2/GLI3-06818 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MBNL2-GLI3 Gene Fusion FISH Probecan detect the fusion of MBNL2 and GLI3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MBNL2-GLI3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
GLI Family Zinc Finger 3 |
Gene Summary 1 |
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 7 |
Locus 1 |
7p14.1 |
Coordinates 1 |
This gene maps to 42000547-42276618 in GRCh37 coordinates. |
Gene Name 2 |
Muscleblind Like Splicing Regulator 2 |
Gene Summary 2 |
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012] |
Chromosome 2 |
Chromosome13 |
Locus 2 |
13q32.1 |
Coordinates 2 |
This gene maps to 97874573-98046374 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MBNL2/GLI3-06818-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MBNL2/GLI3-06818-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MBNL2/GLI3-06818-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MBNL2/GLI3-06818-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MBNL2/GLI3-06818-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MBNL2/GLI3-06818-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MBNL2/GLI3-06818-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MBNL2/GLI3-06818-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MBNL2/GLI3-06818-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MBNL2/GLI3-06818-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MBNL2/GLI3-06818-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MBNL2/GLI3-06818-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MBNL2/GLI3-06818-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MBNL2/GLI3-06818-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MBNL2/GLI3-06818-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MBNL2/GLI3-06818-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MBNL2/GLI3-06818-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MBNL2/GLI3-06818-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MBNL2/GLI3-06818-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MBNL2/GLI3-06818-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MBNL2/GLI3-06818-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MBNL2/GLI3-06818-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MBNL2/GLI3-06818-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MBNL2/GLI3-06818-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MBNL2/GLI3-06818-AQAQ |
467nm;467nm |
418nm;418nm |
|
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