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MAX-RUNX2 Gene Fusion FISH Probe

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Catalog: GFFP-MAX/RUNX2-14299
Classification: Gene Fusion FISH Probes
Description: The MAX-RUNX2 Gene Fusion FISH Probecan detect the fusion of MAX and RUNX2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MAX-RUNX2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Runt Related Transcription Factor 2
Gene Summary 1 This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
Chromosome 1 Chromosome 6
Locus 1 6p21.1
Coordinates 1 This gene maps to 45296053-45518819 in GRCh37 coordinates.
Gene Name 2 MYC Associated Factor X
Gene Summary 2 The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Chromosome 2 Chromosome14
Locus 2 14q23.3
Coordinates 2 This gene maps to 65472891-65569227 in GRCh37 coordinates.
Associated Diseases Head And Neck Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MAX/RUNX2-14299-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MAX/RUNX2-14299-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MAX/RUNX2-14299-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MAX/RUNX2-14299-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MAX/RUNX2-14299-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MAX/RUNX2-14299-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MAX/RUNX2-14299-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MAX/RUNX2-14299-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MAX/RUNX2-14299-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MAX/RUNX2-14299-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MAX/RUNX2-14299-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MAX/RUNX2-14299-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MAX/RUNX2-14299-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MAX/RUNX2-14299-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MAX/RUNX2-14299-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MAX/RUNX2-14299-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MAX/RUNX2-14299-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MAX/RUNX2-14299-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MAX/RUNX2-14299-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MAX/RUNX2-14299-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MAX/RUNX2-14299-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MAX/RUNX2-14299-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MAX/RUNX2-14299-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MAX/RUNX2-14299-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MAX/RUNX2-14299-AQAQ 467nm;467nm 418nm;418nm

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