MARK3-FBLN5 Gene Fusion FISH Probe
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Catalog: |
GFFP-MARK3/FBLN5-06863 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MARK3-FBLN5 Gene Fusion FISH Probecan detect the fusion of MARK3 and FBLN5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MARK3-FBLN5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Microtubule Affinity Regulating Kinase 3 |
Gene Summary 1 |
The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
Chromosome 1 |
Chromosome 14 |
Locus 1 |
14q32.32-q32.33 |
Coordinates 1 |
This gene maps to 103851700-103970166 in GRCh37 coordinates. |
Gene Name 2 |
Fibulin 5 |
Gene Summary 2 |
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome14 |
Locus 2 |
14q32.12 |
Coordinates 2 |
This gene maps to 92335754-92414046 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MARK3/FBLN5-06863-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MARK3/FBLN5-06863-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MARK3/FBLN5-06863-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MARK3/FBLN5-06863-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MARK3/FBLN5-06863-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MARK3/FBLN5-06863-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MARK3/FBLN5-06863-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MARK3/FBLN5-06863-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MARK3/FBLN5-06863-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MARK3/FBLN5-06863-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MARK3/FBLN5-06863-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MARK3/FBLN5-06863-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MARK3/FBLN5-06863-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MARK3/FBLN5-06863-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MARK3/FBLN5-06863-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MARK3/FBLN5-06863-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MARK3/FBLN5-06863-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MARK3/FBLN5-06863-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MARK3/FBLN5-06863-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MARK3/FBLN5-06863-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MARK3/FBLN5-06863-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MARK3/FBLN5-06863-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MARK3/FBLN5-06863-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MARK3/FBLN5-06863-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MARK3/FBLN5-06863-AQAQ |
467nm;467nm |
418nm;418nm |
|
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