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MAPKAPK3-HEMK1 Gene Fusion FISH Probe

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Catalog: GFFP-MAPKAPK3/HEMK1-15284
Classification: Gene Fusion FISH Probes
Description: The MAPKAPK3-HEMK1 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MAPKAPK3-HEMK1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Mitogen-activated Protein Kinase-activated Protein Kinase 3
Gene Summary 1 This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
Chromosome 1 Chromosome 3
Locus 1 3p21.2
Coordinates 1 This gene maps to 50649292-50686728in GRCh37 coordinates.
Gene Name 2 HemK Methyltransferase Family Member 1
Gene Summary 2 The HemK Methyltransferase Family Member 1 (HEMK1) gene is located on chr3 :50606908-50622421 at 3p21.31.
Chromosome 2 Chromosome3
Locus 2 3p21.31
Coordinates 2 This gene maps to 50606908-50622421 in GRCh37 coordinates.
Associated Diseases Liver Hepatocellular Carcinoma; Lung Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MAPKAPK3/HEMK1-15284-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MAPKAPK3/HEMK1-15284-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MAPKAPK3/HEMK1-15284-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MAPKAPK3/HEMK1-15284-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MAPKAPK3/HEMK1-15284-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MAPKAPK3/HEMK1-15284-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MAPKAPK3/HEMK1-15284-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MAPKAPK3/HEMK1-15284-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MAPKAPK3/HEMK1-15284-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MAPKAPK3/HEMK1-15284-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MAPKAPK3/HEMK1-15284-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MAPKAPK3/HEMK1-15284-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MAPKAPK3/HEMK1-15284-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MAPKAPK3/HEMK1-15284-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MAPKAPK3/HEMK1-15284-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MAPKAPK3/HEMK1-15284-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MAPKAPK3/HEMK1-15284-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MAPKAPK3/HEMK1-15284-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MAPKAPK3/HEMK1-15284-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MAPKAPK3/HEMK1-15284-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MAPKAPK3/HEMK1-15284-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MAPKAPK3/HEMK1-15284-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MAPKAPK3/HEMK1-15284-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MAPKAPK3/HEMK1-15284-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MAPKAPK3/HEMK1-15284-AQAQ 467nm;467nm 418nm;418nm

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