MAPK9-DGKB Gene Fusion FISH Probe
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Catalog: |
GFFP-MAPK9/DGKB-06883 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MAPK9-DGKB Gene Fusion FISH Probecan detect the fusion of MAPK9 and DGKB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MAPK9-DGKB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Diacylglycerol Kinase Beta |
Gene Summary 1 |
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017] |
Chromosome 1 |
Chromosome 7 |
Locus 1 |
7p21.2 |
Coordinates 1 |
This gene maps to 14184673-14881075 in GRCh37 coordinates. |
Gene Name 2 |
Mitogen-activated Protein Kinase 9 |
Gene Summary 2 |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008] |
Chromosome 2 |
Chromosome5 |
Locus 2 |
5q35.3 |
Coordinates 2 |
This gene maps to 179660594-179719071 in GRCh37 coordinates. |
Associated Diseases |
Prostate Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MAPK9/DGKB-06883-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MAPK9/DGKB-06883-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MAPK9/DGKB-06883-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MAPK9/DGKB-06883-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MAPK9/DGKB-06883-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MAPK9/DGKB-06883-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MAPK9/DGKB-06883-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MAPK9/DGKB-06883-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MAPK9/DGKB-06883-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MAPK9/DGKB-06883-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MAPK9/DGKB-06883-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MAPK9/DGKB-06883-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MAPK9/DGKB-06883-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MAPK9/DGKB-06883-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MAPK9/DGKB-06883-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MAPK9/DGKB-06883-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MAPK9/DGKB-06883-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MAPK9/DGKB-06883-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MAPK9/DGKB-06883-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MAPK9/DGKB-06883-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MAPK9/DGKB-06883-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MAPK9/DGKB-06883-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MAPK9/DGKB-06883-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MAPK9/DGKB-06883-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MAPK9/DGKB-06883-AQAQ |
467nm;467nm |
418nm;418nm |
|
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