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MAPK9-DGKB Gene Fusion FISH Probe

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Catalog: GFFP-MAPK9/DGKB-06883
Classification: Gene Fusion FISH Probes
Description: The MAPK9-DGKB Gene Fusion FISH Probecan detect the fusion of MAPK9 and DGKB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MAPK9-DGKB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Diacylglycerol Kinase Beta
Gene Summary 1 Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Chromosome 1 Chromosome 7
Locus 1 7p21.2
Coordinates 1 This gene maps to 14184673-14881075 in GRCh37 coordinates.
Gene Name 2 Mitogen-activated Protein Kinase 9
Gene Summary 2 The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
Chromosome 2 Chromosome5
Locus 2 5q35.3
Coordinates 2 This gene maps to 179660594-179719071 in GRCh37 coordinates.
Associated Diseases Prostate Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MAPK9/DGKB-06883-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MAPK9/DGKB-06883-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MAPK9/DGKB-06883-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MAPK9/DGKB-06883-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MAPK9/DGKB-06883-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MAPK9/DGKB-06883-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MAPK9/DGKB-06883-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MAPK9/DGKB-06883-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MAPK9/DGKB-06883-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MAPK9/DGKB-06883-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MAPK9/DGKB-06883-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MAPK9/DGKB-06883-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MAPK9/DGKB-06883-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MAPK9/DGKB-06883-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MAPK9/DGKB-06883-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MAPK9/DGKB-06883-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MAPK9/DGKB-06883-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MAPK9/DGKB-06883-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MAPK9/DGKB-06883-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MAPK9/DGKB-06883-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MAPK9/DGKB-06883-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MAPK9/DGKB-06883-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MAPK9/DGKB-06883-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MAPK9/DGKB-06883-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MAPK9/DGKB-06883-AQAQ 467nm;467nm 418nm;418nm

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