MAP3K8-LYZL2 Gene Fusion FISH Probe
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Catalog: |
GFFP-MAP3K8/LYZL2-06928 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MAP3K8-LYZL2 Gene Fusion FISH Probecan detect the fusion of MAP3K8 and LYZL2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MAP3K8-LYZL2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Mitogen-activated Protein Kinase Kinase Kinase 8 |
Gene Summary 1 |
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011] |
Chromosome 1 |
Chromosome 10 |
Locus 1 |
10p11.23 |
Coordinates 1 |
This gene maps to 30722949-30750762 in GRCh37 coordinates. |
Gene Name 2 |
Lysozyme Like 2 |
Gene Summary 2 |
Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL2 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).[supplied by OMIM, Apr 2009] |
Chromosome 2 |
Chromosome10 |
Locus 2 |
10p11.23 |
Coordinates 2 |
This gene maps to 30900707-30918647 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MAP3K8/LYZL2-06928-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MAP3K8/LYZL2-06928-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MAP3K8/LYZL2-06928-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MAP3K8/LYZL2-06928-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MAP3K8/LYZL2-06928-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MAP3K8/LYZL2-06928-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MAP3K8/LYZL2-06928-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MAP3K8/LYZL2-06928-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MAP3K8/LYZL2-06928-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MAP3K8/LYZL2-06928-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MAP3K8/LYZL2-06928-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MAP3K8/LYZL2-06928-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MAP3K8/LYZL2-06928-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MAP3K8/LYZL2-06928-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MAP3K8/LYZL2-06928-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MAP3K8/LYZL2-06928-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MAP3K8/LYZL2-06928-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MAP3K8/LYZL2-06928-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MAP3K8/LYZL2-06928-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MAP3K8/LYZL2-06928-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MAP3K8/LYZL2-06928-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MAP3K8/LYZL2-06928-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MAP3K8/LYZL2-06928-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MAP3K8/LYZL2-06928-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MAP3K8/LYZL2-06928-AQAQ |
467nm;467nm |
418nm;418nm |
|
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