MAP3K3-FCHSD2 Gene Fusion FISH Probe
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Catalog: |
GFFP-MAP3K3/FCHSD2-06956 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MAP3K3-FCHSD2 Gene Fusion FISH Probecan detect the fusion of MAP3K3 and FCHSD2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MAP3K3-FCHSD2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Mitogen-activated Protein Kinase Kinase Kinase 3 |
Gene Summary 1 |
This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q23.3 |
Coordinates 1 |
This gene maps to 61699800-61773670 in GRCh37 coordinates. |
Gene Name 2 |
FCH And Double SH3 Domains 2 |
Gene Summary 2 |
The FCH And Double SH3 Domains 2 (FCHSD2) gene is located on chr11 :72547789-72853143 at 11q13.4. |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q13.4 |
Coordinates 2 |
This gene maps to 72547789-72853143 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MAP3K3/FCHSD2-06956-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MAP3K3/FCHSD2-06956-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MAP3K3/FCHSD2-06956-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MAP3K3/FCHSD2-06956-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MAP3K3/FCHSD2-06956-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MAP3K3/FCHSD2-06956-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MAP3K3/FCHSD2-06956-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MAP3K3/FCHSD2-06956-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MAP3K3/FCHSD2-06956-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MAP3K3/FCHSD2-06956-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MAP3K3/FCHSD2-06956-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MAP3K3/FCHSD2-06956-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MAP3K3/FCHSD2-06956-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MAP3K3/FCHSD2-06956-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MAP3K3/FCHSD2-06956-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MAP3K3/FCHSD2-06956-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MAP3K3/FCHSD2-06956-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MAP3K3/FCHSD2-06956-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MAP3K3/FCHSD2-06956-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MAP3K3/FCHSD2-06956-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MAP3K3/FCHSD2-06956-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MAP3K3/FCHSD2-06956-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MAP3K3/FCHSD2-06956-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MAP3K3/FCHSD2-06956-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MAP3K3/FCHSD2-06956-AQAQ |
467nm;467nm |
418nm;418nm |
|
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