MAP2K2-RP11-87C12.2 Gene Fusion FISH Probe
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Catalog: |
GFFP-MAP2K2/RP11-87C12.2-14311 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The MAP2K2-RP11-87C12.2 Gene Fusion FISH Probecan detect the fusion of MAP2K2 and RP11-87C12.2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
MAP2K2-RP11-87C12.2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Mitogen-activated Protein Kinase Kinase 2 |
Gene Summary 1 |
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.3 |
Coordinates 1 |
This gene maps to 4090319-4124126 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-MAP2K2/RP11-87C12.2-14311-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-MAP2K2/RP11-87C12.2-14311-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-MAP2K2/RP11-87C12.2-14311-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-MAP2K2/RP11-87C12.2-14311-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-MAP2K2/RP11-87C12.2-14311-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-MAP2K2/RP11-87C12.2-14311-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-MAP2K2/RP11-87C12.2-14311-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-MAP2K2/RP11-87C12.2-14311-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-MAP2K2/RP11-87C12.2-14311-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-MAP2K2/RP11-87C12.2-14311-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-MAP2K2/RP11-87C12.2-14311-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-MAP2K2/RP11-87C12.2-14311-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-MAP2K2/RP11-87C12.2-14311-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-MAP2K2/RP11-87C12.2-14311-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-MAP2K2/RP11-87C12.2-14311-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-MAP2K2/RP11-87C12.2-14311-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-MAP2K2/RP11-87C12.2-14311-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-MAP2K2/RP11-87C12.2-14311-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-MAP2K2/RP11-87C12.2-14311-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-MAP2K2/RP11-87C12.2-14311-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-MAP2K2/RP11-87C12.2-14311-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-MAP2K2/RP11-87C12.2-14311-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-MAP2K2/RP11-87C12.2-14311-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-MAP2K2/RP11-87C12.2-14311-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-MAP2K2/RP11-87C12.2-14311-AQAQ |
467nm;467nm |
418nm;418nm |
|
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