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MADD-PIK3C2A Gene Fusion FISH Probe

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Catalog: GFFP-MADD/PIK3C2A-06705
Classification: Gene Fusion FISH Probes
Description: The MADD-PIK3C2A Gene Fusion FISH Probecan detect the fusion of MADD and PIK3C2A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: MADD-PIK3C2A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Phosphatidylinositol-4-phosphate 3-kinase Catalytic Subunit Type 2 Alpha
Gene Summary 1 The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 11
Locus 1 11p15.1
Coordinates 1 This gene maps to 17108123-17191354 in GRCh37 coordinates.
Gene Name 2 MAP Kinase Activating Death Domain
Gene Summary 2 Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome11
Locus 2 11p11.2
Coordinates 2 This gene maps to 47290926-47351582 in GRCh37 coordinates.
Associated Diseases Bladder Urothelial Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-MADD/PIK3C2A-06705-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-MADD/PIK3C2A-06705-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-MADD/PIK3C2A-06705-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-MADD/PIK3C2A-06705-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-MADD/PIK3C2A-06705-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-MADD/PIK3C2A-06705-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-MADD/PIK3C2A-06705-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-MADD/PIK3C2A-06705-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-MADD/PIK3C2A-06705-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-MADD/PIK3C2A-06705-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-MADD/PIK3C2A-06705-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-MADD/PIK3C2A-06705-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-MADD/PIK3C2A-06705-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-MADD/PIK3C2A-06705-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-MADD/PIK3C2A-06705-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-MADD/PIK3C2A-06705-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-MADD/PIK3C2A-06705-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-MADD/PIK3C2A-06705-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-MADD/PIK3C2A-06705-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-MADD/PIK3C2A-06705-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-MADD/PIK3C2A-06705-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-MADD/PIK3C2A-06705-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-MADD/PIK3C2A-06705-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-MADD/PIK3C2A-06705-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-MADD/PIK3C2A-06705-AQAQ 467nm;467nm 418nm;418nm

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