LRSAM1-DENND1A Gene Fusion FISH Probe
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Catalog: |
GFFP-LRSAM1/DENND1A-06776 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The LRSAM1-DENND1A Gene Fusion FISH Probecan detect the fusion of LRSAM1 and DENND1A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
LRSAM1-DENND1A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DENN Domain Containing 1A |
Gene Summary 1 |
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010] |
Chromosome 1 |
Chromosome 9 |
Locus 1 |
9q33.3 |
Coordinates 1 |
This gene maps to 126141932-126692417 in GRCh37 coordinates. |
Gene Name 2 |
Leucine Rich Repeat And Sterile Alpha Motif Containing 1 |
Gene Summary 2 |
This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9q33.3-q34.11 |
Coordinates 2 |
This gene maps to 130213764-130265780 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-LRSAM1/DENND1A-06776-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-LRSAM1/DENND1A-06776-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-LRSAM1/DENND1A-06776-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-LRSAM1/DENND1A-06776-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-LRSAM1/DENND1A-06776-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-LRSAM1/DENND1A-06776-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-LRSAM1/DENND1A-06776-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-LRSAM1/DENND1A-06776-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-LRSAM1/DENND1A-06776-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-LRSAM1/DENND1A-06776-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-LRSAM1/DENND1A-06776-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-LRSAM1/DENND1A-06776-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-LRSAM1/DENND1A-06776-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-LRSAM1/DENND1A-06776-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-LRSAM1/DENND1A-06776-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-LRSAM1/DENND1A-06776-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-LRSAM1/DENND1A-06776-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-LRSAM1/DENND1A-06776-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-LRSAM1/DENND1A-06776-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-LRSAM1/DENND1A-06776-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-LRSAM1/DENND1A-06776-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-LRSAM1/DENND1A-06776-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-LRSAM1/DENND1A-06776-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-LRSAM1/DENND1A-06776-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-LRSAM1/DENND1A-06776-AQAQ |
467nm;467nm |
418nm;418nm |
|
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