LRRK2-GXYLT1 Gene Fusion FISH Probe
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| Catalog: |
GFFP-LRRK2/GXYLT1-06782 |
| Classification: |
Gene Fusion FISH Probes |
| Description: |
The LRRK2-GXYLT1 Gene Fusion FISH Probecan detect the fusion of LRRK2 and GXYLT1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Category: |
Gene Fusion FISH Probes |
| Application: |
LRRK2-GXYLT1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name 1 |
Leucine Rich Repeat Kinase 2 |
| Gene Summary 1 |
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008] |
| Chromosome 1 |
Chromosome 12 |
| Locus 1 |
12q12 |
| Coordinates 1 |
This gene maps to 40618812-40763086 in GRCh37 coordinates. |
| Gene Name 2 |
Glucoside Xylosyltransferase 1 |
| Gene Summary 2 |
GXYLT1 is a xylosyltransferase (EC 2.4.2.-) that adds the first xylose to O-glucose-modified residues in the epidermal growth factor (EGF; MIM 131530) repeats of proteins such as NOTCH1 (MIM 190198) (Sethi et al., 2010 [PubMed 19940119]).[supplied by OMIM, Mar 2010] |
| Chromosome 2 |
Chromosome12 |
| Locus 2 |
12q12 |
| Coordinates 2 |
This gene maps to 42475647-42538673 in GRCh37 coordinates. |
| Associated Diseases |
Brain Lower Grade Glioma |
| Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
RE; RE
|
GFFP-LRRK2/GXYLT1-06782-RERE |
599nm;599nm |
580nm;580nm |
|
| 2 |
RE; OR
|
GFFP-LRRK2/GXYLT1-06782-REOR |
599nm;573nm |
580nm;548nm |
|
| 3 |
RE; GO
|
GFFP-LRRK2/GXYLT1-06782-REGO |
599nm;551nm |
580nm;525nm |
|
| 4 |
RE; GR
|
GFFP-LRRK2/GXYLT1-06782-REGR |
599nm;515nm |
580nm;491nm |
|
| 5 |
RE; AQ
|
GFFP-LRRK2/GXYLT1-06782-REAQ |
599nm;467nm |
580nm;418nm |
|
| 6 |
OR; RE
|
GFFP-LRRK2/GXYLT1-06782-ORRE |
573nm;599nm |
548nm;580nm |
|
| 7 |
OR; OR
|
GFFP-LRRK2/GXYLT1-06782-OROR |
573nm;573nm |
548nm;548nm |
|
| 8 |
OR; GO
|
GFFP-LRRK2/GXYLT1-06782-ORGO |
573nm;551nm |
548nm;525nm |
|
| 9 |
OR; GR
|
GFFP-LRRK2/GXYLT1-06782-ORGR |
573nm;515nm |
548nm;491nm |
|
| 10 |
OR; AQ
|
GFFP-LRRK2/GXYLT1-06782-ORAQ |
573nm;467nm |
548nm;418nm |
|
| 11 |
GO; RE
|
GFFP-LRRK2/GXYLT1-06782-GORE |
551nm;599nm |
525nm;580nm |
|
| 12 |
GO; OR
|
GFFP-LRRK2/GXYLT1-06782-GOOR |
551nm;573nm |
525nm;548nm |
|
| 13 |
GO; GO
|
GFFP-LRRK2/GXYLT1-06782-GOGO |
551nm;551nm |
525nm;525nm |
|
| 14 |
GO; GR
|
GFFP-LRRK2/GXYLT1-06782-GOGR |
551nm;515nm |
525nm;491nm |
|
| 15 |
GO; AQ
|
GFFP-LRRK2/GXYLT1-06782-GOAQ |
551nm;467nm |
525nm;418nm |
|
| 16 |
GR; RE
|
GFFP-LRRK2/GXYLT1-06782-GRRE |
515nm;599nm |
491nm;580nm |
|
| 17 |
GR; OR
|
GFFP-LRRK2/GXYLT1-06782-GROR |
515nm;573nm |
491nm;548nm |
|
| 18 |
GR; GO
|
GFFP-LRRK2/GXYLT1-06782-GRGO |
515nm;551nm |
491nm;525nm |
|
| 19 |
GR; GR
|
GFFP-LRRK2/GXYLT1-06782-GRGR |
515nm;515nm |
491nm;491nm |
|
| 20 |
GR; AQ
|
GFFP-LRRK2/GXYLT1-06782-GRAQ |
515nm;467nm |
491nm;418nm |
|
| 21 |
AQ; RE
|
GFFP-LRRK2/GXYLT1-06782-AQRE |
467nm;599nm |
418nm;580nm |
|
| 22 |
AQ; OR
|
GFFP-LRRK2/GXYLT1-06782-AQOR |
467nm;573nm |
418nm;548nm |
|
| 23 |
AQ; GO
|
GFFP-LRRK2/GXYLT1-06782-AQGO |
467nm;551nm |
418nm;525nm |
|
| 24 |
AQ; GR
|
GFFP-LRRK2/GXYLT1-06782-AQGR |
467nm;515nm |
418nm;491nm |
|
| 25 |
AQ; AQ
|
GFFP-LRRK2/GXYLT1-06782-AQAQ |
467nm;467nm |
418nm;418nm |
|
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