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LRRFIP2-EPHA3 Gene Fusion FISH Probe

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Catalog: GFFP-LRRFIP2/EPHA3-06783
Classification: Gene Fusion FISH Probes
Description: The LRRFIP2-EPHA3 Gene Fusion FISH Probecan detect the fusion of LRRFIP2 and EPHA3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: LRRFIP2-EPHA3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 EPH Receptor A3
Gene Summary 1 This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 3
Locus 1 3p11.1
Coordinates 1 This gene maps to 89156673-89531284 in GRCh37 coordinates.
Gene Name 2 LRR Binding FLII Interacting Protein 2
Gene Summary 2 The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
Chromosome 2 Chromosome3
Locus 2 3p22.2
Coordinates 2 This gene maps to 37094116-37217851 in GRCh37 coordinates.
Associated Diseases Stomach Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-LRRFIP2/EPHA3-06783-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-LRRFIP2/EPHA3-06783-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-LRRFIP2/EPHA3-06783-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-LRRFIP2/EPHA3-06783-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-LRRFIP2/EPHA3-06783-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-LRRFIP2/EPHA3-06783-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-LRRFIP2/EPHA3-06783-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-LRRFIP2/EPHA3-06783-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-LRRFIP2/EPHA3-06783-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-LRRFIP2/EPHA3-06783-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-LRRFIP2/EPHA3-06783-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-LRRFIP2/EPHA3-06783-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-LRRFIP2/EPHA3-06783-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-LRRFIP2/EPHA3-06783-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-LRRFIP2/EPHA3-06783-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-LRRFIP2/EPHA3-06783-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-LRRFIP2/EPHA3-06783-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-LRRFIP2/EPHA3-06783-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-LRRFIP2/EPHA3-06783-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-LRRFIP2/EPHA3-06783-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-LRRFIP2/EPHA3-06783-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-LRRFIP2/EPHA3-06783-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-LRRFIP2/EPHA3-06783-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-LRRFIP2/EPHA3-06783-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-LRRFIP2/EPHA3-06783-AQAQ 467nm;467nm 418nm;418nm

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