LRRFIP2-EPHA3 Gene Fusion FISH Probe
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Catalog: |
GFFP-LRRFIP2/EPHA3-06783 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The LRRFIP2-EPHA3 Gene Fusion FISH Probecan detect the fusion of LRRFIP2 and EPHA3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
LRRFIP2-EPHA3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
EPH Receptor A3 |
Gene Summary 1 |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3p11.1 |
Coordinates 1 |
This gene maps to 89156673-89531284 in GRCh37 coordinates. |
Gene Name 2 |
LRR Binding FLII Interacting Protein 2 |
Gene Summary 2 |
The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017] |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3p22.2 |
Coordinates 2 |
This gene maps to 37094116-37217851 in GRCh37 coordinates. |
Associated Diseases |
Stomach Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-LRRFIP2/EPHA3-06783-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-LRRFIP2/EPHA3-06783-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-LRRFIP2/EPHA3-06783-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-LRRFIP2/EPHA3-06783-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-LRRFIP2/EPHA3-06783-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-LRRFIP2/EPHA3-06783-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-LRRFIP2/EPHA3-06783-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-LRRFIP2/EPHA3-06783-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-LRRFIP2/EPHA3-06783-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-LRRFIP2/EPHA3-06783-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-LRRFIP2/EPHA3-06783-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-LRRFIP2/EPHA3-06783-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-LRRFIP2/EPHA3-06783-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-LRRFIP2/EPHA3-06783-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-LRRFIP2/EPHA3-06783-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-LRRFIP2/EPHA3-06783-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-LRRFIP2/EPHA3-06783-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-LRRFIP2/EPHA3-06783-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-LRRFIP2/EPHA3-06783-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-LRRFIP2/EPHA3-06783-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-LRRFIP2/EPHA3-06783-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-LRRFIP2/EPHA3-06783-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-LRRFIP2/EPHA3-06783-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-LRRFIP2/EPHA3-06783-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-LRRFIP2/EPHA3-06783-AQAQ |
467nm;467nm |
418nm;418nm |
|
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