LRP6-PTPRO Gene Fusion FISH Probe
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| Catalog: |
GFFP-LRP6/PTPRO-06503 |
| Classification: |
Gene Fusion FISH Probes |
| Description: |
The LRP6-PTPRO Gene Fusion FISH Probecan detect the fusion of LRP6 and PTPRO genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Category: |
Gene Fusion FISH Probes |
| Application: |
LRP6-PTPRO Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name 1 |
LDL Receptor Related Protein 6 |
| Gene Summary 1 |
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009] |
| Chromosome 1 |
Chromosome 12 |
| Locus 1 |
12p13.2 |
| Coordinates 1 |
This gene maps to 12268960-12419811 in GRCh37 coordinates. |
| Gene Name 2 |
Protein Tyrosine Phosphatase, Receptor Type O |
| Gene Summary 2 |
This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011] |
| Chromosome 2 |
Chromosome12 |
| Locus 2 |
12p13-p12 |
| Coordinates 2 |
This gene maps to 15475190-15751265 in GRCh37 coordinates. |
| Associated Diseases |
Pancreatic Adenocarcinoma |
| Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
RE; RE
|
GFFP-LRP6/PTPRO-06503-RERE |
599nm;599nm |
580nm;580nm |
|
| 2 |
RE; OR
|
GFFP-LRP6/PTPRO-06503-REOR |
599nm;573nm |
580nm;548nm |
|
| 3 |
RE; GO
|
GFFP-LRP6/PTPRO-06503-REGO |
599nm;551nm |
580nm;525nm |
|
| 4 |
RE; GR
|
GFFP-LRP6/PTPRO-06503-REGR |
599nm;515nm |
580nm;491nm |
|
| 5 |
RE; AQ
|
GFFP-LRP6/PTPRO-06503-REAQ |
599nm;467nm |
580nm;418nm |
|
| 6 |
OR; RE
|
GFFP-LRP6/PTPRO-06503-ORRE |
573nm;599nm |
548nm;580nm |
|
| 7 |
OR; OR
|
GFFP-LRP6/PTPRO-06503-OROR |
573nm;573nm |
548nm;548nm |
|
| 8 |
OR; GO
|
GFFP-LRP6/PTPRO-06503-ORGO |
573nm;551nm |
548nm;525nm |
|
| 9 |
OR; GR
|
GFFP-LRP6/PTPRO-06503-ORGR |
573nm;515nm |
548nm;491nm |
|
| 10 |
OR; AQ
|
GFFP-LRP6/PTPRO-06503-ORAQ |
573nm;467nm |
548nm;418nm |
|
| 11 |
GO; RE
|
GFFP-LRP6/PTPRO-06503-GORE |
551nm;599nm |
525nm;580nm |
|
| 12 |
GO; OR
|
GFFP-LRP6/PTPRO-06503-GOOR |
551nm;573nm |
525nm;548nm |
|
| 13 |
GO; GO
|
GFFP-LRP6/PTPRO-06503-GOGO |
551nm;551nm |
525nm;525nm |
|
| 14 |
GO; GR
|
GFFP-LRP6/PTPRO-06503-GOGR |
551nm;515nm |
525nm;491nm |
|
| 15 |
GO; AQ
|
GFFP-LRP6/PTPRO-06503-GOAQ |
551nm;467nm |
525nm;418nm |
|
| 16 |
GR; RE
|
GFFP-LRP6/PTPRO-06503-GRRE |
515nm;599nm |
491nm;580nm |
|
| 17 |
GR; OR
|
GFFP-LRP6/PTPRO-06503-GROR |
515nm;573nm |
491nm;548nm |
|
| 18 |
GR; GO
|
GFFP-LRP6/PTPRO-06503-GRGO |
515nm;551nm |
491nm;525nm |
|
| 19 |
GR; GR
|
GFFP-LRP6/PTPRO-06503-GRGR |
515nm;515nm |
491nm;491nm |
|
| 20 |
GR; AQ
|
GFFP-LRP6/PTPRO-06503-GRAQ |
515nm;467nm |
491nm;418nm |
|
| 21 |
AQ; RE
|
GFFP-LRP6/PTPRO-06503-AQRE |
467nm;599nm |
418nm;580nm |
|
| 22 |
AQ; OR
|
GFFP-LRP6/PTPRO-06503-AQOR |
467nm;573nm |
418nm;548nm |
|
| 23 |
AQ; GO
|
GFFP-LRP6/PTPRO-06503-AQGO |
467nm;551nm |
418nm;525nm |
|
| 24 |
AQ; GR
|
GFFP-LRP6/PTPRO-06503-AQGR |
467nm;515nm |
418nm;491nm |
|
| 25 |
AQ; AQ
|
GFFP-LRP6/PTPRO-06503-AQAQ |
467nm;467nm |
418nm;418nm |
|
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