LRP5-VPS37C Gene Fusion FISH Probe
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Catalog: |
GFFP-LRP5/VPS37C-06507 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The LRP5-VPS37C Gene Fusion FISH Probecan detect the fusion of LRP5 and VPS37C genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
LRP5-VPS37C Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
LDL Receptor Related Protein 5 |
Gene Summary 1 |
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q13.2 |
Coordinates 1 |
This gene maps to 68080107-68216743 in GRCh37 coordinates. |
Gene Name 2 |
VPS37C, ESCRT-I Subunit |
Gene Summary 2 |
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q12.2 |
Coordinates 2 |
This gene maps to 60897727-60928916 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-LRP5/VPS37C-06507-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-LRP5/VPS37C-06507-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-LRP5/VPS37C-06507-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-LRP5/VPS37C-06507-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-LRP5/VPS37C-06507-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-LRP5/VPS37C-06507-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-LRP5/VPS37C-06507-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-LRP5/VPS37C-06507-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-LRP5/VPS37C-06507-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-LRP5/VPS37C-06507-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-LRP5/VPS37C-06507-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-LRP5/VPS37C-06507-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-LRP5/VPS37C-06507-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-LRP5/VPS37C-06507-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-LRP5/VPS37C-06507-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-LRP5/VPS37C-06507-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-LRP5/VPS37C-06507-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-LRP5/VPS37C-06507-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-LRP5/VPS37C-06507-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-LRP5/VPS37C-06507-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-LRP5/VPS37C-06507-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-LRP5/VPS37C-06507-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-LRP5/VPS37C-06507-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-LRP5/VPS37C-06507-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-LRP5/VPS37C-06507-AQAQ |
467nm;467nm |
418nm;418nm |
|
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