LRP1-XPO5 Gene Fusion FISH Probe
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Catalog: |
GFFP-LRP1/XPO5-06522 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The LRP1-XPO5 Gene Fusion FISH Probecan detect the fusion of LRP1 and XPO5 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
LRP1-XPO5 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
LDL Receptor Related Protein 1 |
Gene Summary 1 |
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q13.3 |
Coordinates 1 |
This gene maps to 57522281-57607125 in GRCh37 coordinates. |
Gene Name 2 |
Exportin 5 |
Gene Summary 2 |
This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process. [provided by RefSeq, Aug 2011] |
Chromosome 2 |
Chromosome6 |
Locus 2 |
6p21.1 |
Coordinates 2 |
This gene maps to 43490067-43543812 in GRCh37 coordinates. |
Associated Diseases |
Glioblastoma Multiforme |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-LRP1/XPO5-06522-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-LRP1/XPO5-06522-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-LRP1/XPO5-06522-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-LRP1/XPO5-06522-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-LRP1/XPO5-06522-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-LRP1/XPO5-06522-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-LRP1/XPO5-06522-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-LRP1/XPO5-06522-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-LRP1/XPO5-06522-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-LRP1/XPO5-06522-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-LRP1/XPO5-06522-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-LRP1/XPO5-06522-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-LRP1/XPO5-06522-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-LRP1/XPO5-06522-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-LRP1/XPO5-06522-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-LRP1/XPO5-06522-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-LRP1/XPO5-06522-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-LRP1/XPO5-06522-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-LRP1/XPO5-06522-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-LRP1/XPO5-06522-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-LRP1/XPO5-06522-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-LRP1/XPO5-06522-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-LRP1/XPO5-06522-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-LRP1/XPO5-06522-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-LRP1/XPO5-06522-AQAQ |
467nm;467nm |
418nm;418nm |
|
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