LAMA3-CABLES1 Gene Fusion FISH Probe
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Catalog: |
GFFP-LAMA3/CABLES1-06418 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The LAMA3-CABLES1 Gene Fusion FISH Probecan detect the fusion of LAMA3 and CABLES1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
LAMA3-CABLES1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Laminin Subunit Alpha 3 |
Gene Summary 1 |
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014] |
Chromosome 1 |
Chromosome 18 |
Locus 1 |
18q11.2 |
Coordinates 1 |
This gene maps to 21269561-21535029 in GRCh37 coordinates. |
Gene Name 2 |
Cdk5 And Abl Enzyme Substrate 1 |
Gene Summary 2 |
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
Chromosome 2 |
Chromosome18 |
Locus 2 |
18q11.2 |
Coordinates 2 |
This gene maps to 20714527-20840434 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-LAMA3/CABLES1-06418-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-LAMA3/CABLES1-06418-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-LAMA3/CABLES1-06418-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-LAMA3/CABLES1-06418-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-LAMA3/CABLES1-06418-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-LAMA3/CABLES1-06418-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-LAMA3/CABLES1-06418-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-LAMA3/CABLES1-06418-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-LAMA3/CABLES1-06418-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-LAMA3/CABLES1-06418-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-LAMA3/CABLES1-06418-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-LAMA3/CABLES1-06418-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-LAMA3/CABLES1-06418-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-LAMA3/CABLES1-06418-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-LAMA3/CABLES1-06418-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-LAMA3/CABLES1-06418-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-LAMA3/CABLES1-06418-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-LAMA3/CABLES1-06418-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-LAMA3/CABLES1-06418-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-LAMA3/CABLES1-06418-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-LAMA3/CABLES1-06418-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-LAMA3/CABLES1-06418-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-LAMA3/CABLES1-06418-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-LAMA3/CABLES1-06418-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-LAMA3/CABLES1-06418-AQAQ |
467nm;467nm |
418nm;418nm |
|
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