KRT19-CLDN7 Gene Fusion FISH Probe
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Catalog: |
GFFP-KRT19/CLDN7-14252 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KRT19-CLDN7 Gene Fusion FISH Probecan detect the fusion of KRT19 and CLDN7 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KRT19-CLDN7 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Claudin 7 |
Gene Summary 1 |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17p13.1 |
Coordinates 1 |
This gene maps to 7163221-7166512 in GRCh37 coordinates. |
Gene Name 2 |
Keratin 19 |
Gene Summary 2 |
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q21.2 |
Coordinates 2 |
This gene maps to 39679868-39684641 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KRT19/CLDN7-14252-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KRT19/CLDN7-14252-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KRT19/CLDN7-14252-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KRT19/CLDN7-14252-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KRT19/CLDN7-14252-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KRT19/CLDN7-14252-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KRT19/CLDN7-14252-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KRT19/CLDN7-14252-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KRT19/CLDN7-14252-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KRT19/CLDN7-14252-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KRT19/CLDN7-14252-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KRT19/CLDN7-14252-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KRT19/CLDN7-14252-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KRT19/CLDN7-14252-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KRT19/CLDN7-14252-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KRT19/CLDN7-14252-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KRT19/CLDN7-14252-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KRT19/CLDN7-14252-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KRT19/CLDN7-14252-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KRT19/CLDN7-14252-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KRT19/CLDN7-14252-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KRT19/CLDN7-14252-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KRT19/CLDN7-14252-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KRT19/CLDN7-14252-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KRT19/CLDN7-14252-AQAQ |
467nm;467nm |
418nm;418nm |
|
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