KPNB1-SKAP1 Gene Fusion FISH Probe
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Catalog: |
GFFP-KPNB1/SKAP1-06453 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KPNB1-SKAP1 Gene Fusion FISH Probecan detect the fusion of KPNB1 and SKAP1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KPNB1-SKAP1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Karyopherin Subunit Beta 1 |
Gene Summary 1 |
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q21.32 |
Coordinates 1 |
This gene maps to 45727274-45761004 in GRCh37 coordinates. |
Gene Name 2 |
Src Kinase Associated Phosphoprotein 1 |
Gene Summary 2 |
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q21.32 |
Coordinates 2 |
This gene maps to 46210801-46507594 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KPNB1/SKAP1-06453-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KPNB1/SKAP1-06453-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KPNB1/SKAP1-06453-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KPNB1/SKAP1-06453-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KPNB1/SKAP1-06453-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KPNB1/SKAP1-06453-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KPNB1/SKAP1-06453-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KPNB1/SKAP1-06453-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KPNB1/SKAP1-06453-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KPNB1/SKAP1-06453-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KPNB1/SKAP1-06453-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KPNB1/SKAP1-06453-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KPNB1/SKAP1-06453-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KPNB1/SKAP1-06453-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KPNB1/SKAP1-06453-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KPNB1/SKAP1-06453-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KPNB1/SKAP1-06453-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KPNB1/SKAP1-06453-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KPNB1/SKAP1-06453-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KPNB1/SKAP1-06453-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KPNB1/SKAP1-06453-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KPNB1/SKAP1-06453-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KPNB1/SKAP1-06453-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KPNB1/SKAP1-06453-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KPNB1/SKAP1-06453-AQAQ |
467nm;467nm |
418nm;418nm |
|
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