KDM4C-KLK7 Gene Fusion FISH Probe
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Catalog: |
GFFP-KDM4C/KLK7-06130 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KDM4C-KLK7 Gene Fusion FISH Probecan detect the fusion of KDM4C and KLK7 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KDM4C-KLK7 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Kallikrein Related Peptidase 7 |
Gene Summary 1 |
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19q13.41 |
Coordinates 1 |
This gene maps to 51479734-51487320 in GRCh37 coordinates. |
Gene Name 2 |
Lysine Demethylase 4C |
Gene Summary 2 |
This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
Chromosome 2 |
Chromosome9 |
Locus 2 |
9p24.1 |
Coordinates 2 |
This gene maps to 6757640-7175648 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KDM4C/KLK7-06130-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KDM4C/KLK7-06130-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KDM4C/KLK7-06130-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KDM4C/KLK7-06130-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KDM4C/KLK7-06130-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KDM4C/KLK7-06130-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KDM4C/KLK7-06130-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KDM4C/KLK7-06130-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KDM4C/KLK7-06130-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KDM4C/KLK7-06130-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KDM4C/KLK7-06130-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KDM4C/KLK7-06130-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KDM4C/KLK7-06130-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KDM4C/KLK7-06130-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KDM4C/KLK7-06130-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KDM4C/KLK7-06130-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KDM4C/KLK7-06130-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KDM4C/KLK7-06130-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KDM4C/KLK7-06130-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KDM4C/KLK7-06130-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KDM4C/KLK7-06130-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KDM4C/KLK7-06130-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KDM4C/KLK7-06130-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KDM4C/KLK7-06130-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KDM4C/KLK7-06130-AQAQ |
467nm;467nm |
418nm;418nm |
|
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