KDM2A-MAP3K3 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-KDM2A/MAP3K3-06159 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KDM2A-MAP3K3 Gene Fusion FISH Probecan detect the fusion of KDM2A and MAP3K3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KDM2A-MAP3K3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Mitogen-activated Protein Kinase Kinase Kinase 3 |
Gene Summary 1 |
This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q23.3 |
Coordinates 1 |
This gene maps to 61699800-61773670 in GRCh37 coordinates. |
Gene Name 2 |
Lysine Demethylase 2A |
Gene Summary 2 |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q13.2 |
Coordinates 2 |
This gene maps to 66886739-67025550 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KDM2A/MAP3K3-06159-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KDM2A/MAP3K3-06159-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KDM2A/MAP3K3-06159-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KDM2A/MAP3K3-06159-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KDM2A/MAP3K3-06159-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KDM2A/MAP3K3-06159-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KDM2A/MAP3K3-06159-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KDM2A/MAP3K3-06159-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KDM2A/MAP3K3-06159-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KDM2A/MAP3K3-06159-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KDM2A/MAP3K3-06159-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KDM2A/MAP3K3-06159-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KDM2A/MAP3K3-06159-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KDM2A/MAP3K3-06159-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KDM2A/MAP3K3-06159-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KDM2A/MAP3K3-06159-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KDM2A/MAP3K3-06159-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KDM2A/MAP3K3-06159-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KDM2A/MAP3K3-06159-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KDM2A/MAP3K3-06159-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KDM2A/MAP3K3-06159-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KDM2A/MAP3K3-06159-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KDM2A/MAP3K3-06159-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KDM2A/MAP3K3-06159-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KDM2A/MAP3K3-06159-AQAQ |
467nm;467nm |
418nm;418nm |
|
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