KDM2A-DDR2 Gene Fusion FISH Probe
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Catalog: |
GFFP-KDM2A/DDR2-05860 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KDM2A-DDR2 Gene Fusion FISH Probecan detect the fusion of KDM2A and DDR2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KDM2A-DDR2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Discoidin Domain Receptor Tyrosine Kinase 2 |
Gene Summary 1 |
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. [provided by RefSeq, Aug 2017] |
Chromosome 1 |
Chromosome 1 |
Locus 1 |
1q23.3 |
Coordinates 1 |
This gene maps to 162602227-162750247 in GRCh37 coordinates. |
Gene Name 2 |
Lysine Demethylase 2A |
Gene Summary 2 |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11q13.2 |
Coordinates 2 |
This gene maps to 66886739-67025550 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KDM2A/DDR2-05860-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KDM2A/DDR2-05860-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KDM2A/DDR2-05860-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KDM2A/DDR2-05860-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KDM2A/DDR2-05860-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KDM2A/DDR2-05860-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KDM2A/DDR2-05860-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KDM2A/DDR2-05860-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KDM2A/DDR2-05860-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KDM2A/DDR2-05860-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KDM2A/DDR2-05860-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KDM2A/DDR2-05860-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KDM2A/DDR2-05860-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KDM2A/DDR2-05860-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KDM2A/DDR2-05860-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KDM2A/DDR2-05860-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KDM2A/DDR2-05860-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KDM2A/DDR2-05860-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KDM2A/DDR2-05860-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KDM2A/DDR2-05860-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KDM2A/DDR2-05860-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KDM2A/DDR2-05860-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KDM2A/DDR2-05860-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KDM2A/DDR2-05860-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KDM2A/DDR2-05860-AQAQ |
467nm;467nm |
418nm;418nm |
|
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