KCNQ1-TSPAN32 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-KCNQ1/TSPAN32-05878 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KCNQ1-TSPAN32 Gene Fusion FISH Probecan detect the fusion of KCNQ1 and TSPAN32 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KCNQ1-TSPAN32 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Potassium Voltage-gated Channel Subfamily Q Member 1 |
Gene Summary 1 |
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11p15.5-p15.4 |
Coordinates 1 |
This gene maps to 2466220-2870340 in GRCh37 coordinates. |
Gene Name 2 |
Tetraspanin 32 |
Gene Summary 2 |
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11p15.5 |
Coordinates 2 |
This gene maps to 2323242-2339430 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KCNQ1/TSPAN32-05878-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KCNQ1/TSPAN32-05878-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KCNQ1/TSPAN32-05878-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KCNQ1/TSPAN32-05878-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KCNQ1/TSPAN32-05878-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KCNQ1/TSPAN32-05878-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KCNQ1/TSPAN32-05878-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KCNQ1/TSPAN32-05878-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KCNQ1/TSPAN32-05878-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KCNQ1/TSPAN32-05878-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KCNQ1/TSPAN32-05878-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KCNQ1/TSPAN32-05878-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KCNQ1/TSPAN32-05878-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KCNQ1/TSPAN32-05878-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KCNQ1/TSPAN32-05878-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KCNQ1/TSPAN32-05878-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KCNQ1/TSPAN32-05878-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KCNQ1/TSPAN32-05878-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KCNQ1/TSPAN32-05878-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KCNQ1/TSPAN32-05878-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KCNQ1/TSPAN32-05878-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KCNQ1/TSPAN32-05878-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KCNQ1/TSPAN32-05878-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KCNQ1/TSPAN32-05878-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KCNQ1/TSPAN32-05878-AQAQ |
467nm;467nm |
418nm;418nm |
|
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