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KCNN3-YEATS4 Gene Fusion FISH Probe

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Catalog: GFFP-KCNN3/YEATS4-05888
Classification: Gene Fusion FISH Probes
Description: The KCNN3-YEATS4 Gene Fusion FISH Probecan detect the fusion of KCNN3 and YEATS4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: KCNN3-YEATS4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Potassium Calcium-activated Channel Subfamily N Member 3
Gene Summary 1 Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Chromosome 1 Chromosome 1
Locus 1 1q21.3
Coordinates 1 This gene maps to 154669941-154842754 in GRCh37 coordinates.
Gene Name 2 YEATS Domain Containing 4
Gene Summary 2 The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Chromosome 2 Chromosome12
Locus 2 12q15
Coordinates 2 This gene maps to 69753531-69784576 in GRCh37 coordinates.
Associated Diseases Sarcoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-KCNN3/YEATS4-05888-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-KCNN3/YEATS4-05888-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-KCNN3/YEATS4-05888-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-KCNN3/YEATS4-05888-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-KCNN3/YEATS4-05888-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-KCNN3/YEATS4-05888-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-KCNN3/YEATS4-05888-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-KCNN3/YEATS4-05888-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-KCNN3/YEATS4-05888-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-KCNN3/YEATS4-05888-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-KCNN3/YEATS4-05888-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-KCNN3/YEATS4-05888-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-KCNN3/YEATS4-05888-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-KCNN3/YEATS4-05888-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-KCNN3/YEATS4-05888-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-KCNN3/YEATS4-05888-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-KCNN3/YEATS4-05888-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-KCNN3/YEATS4-05888-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-KCNN3/YEATS4-05888-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-KCNN3/YEATS4-05888-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-KCNN3/YEATS4-05888-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-KCNN3/YEATS4-05888-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-KCNN3/YEATS4-05888-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-KCNN3/YEATS4-05888-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-KCNN3/YEATS4-05888-AQAQ 467nm;467nm 418nm;418nm

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