KCNMB4-GDF3 Gene Fusion FISH Probe
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Catalog: |
GFFP-KCNMB4/GDF3-05890 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KCNMB4-GDF3 Gene Fusion FISH Probecan detect the fusion of KCNMB4 and GDF3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KCNMB4-GDF3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Growth Differentiation Factor 3 |
Gene Summary 1 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12p13.31 |
Coordinates 1 |
This gene maps to 7842380-7848360 in GRCh37 coordinates. |
Gene Name 2 |
Potassium Calcium-activated Channel Subfamily M Regulatory Beta Subunit 4 |
Gene Summary 2 |
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12q15 |
Coordinates 2 |
This gene maps to 70760061-70828072 in GRCh37 coordinates. |
Associated Diseases |
Sarcoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KCNMB4/GDF3-05890-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KCNMB4/GDF3-05890-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KCNMB4/GDF3-05890-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KCNMB4/GDF3-05890-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KCNMB4/GDF3-05890-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KCNMB4/GDF3-05890-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KCNMB4/GDF3-05890-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KCNMB4/GDF3-05890-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KCNMB4/GDF3-05890-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KCNMB4/GDF3-05890-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KCNMB4/GDF3-05890-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KCNMB4/GDF3-05890-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KCNMB4/GDF3-05890-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KCNMB4/GDF3-05890-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KCNMB4/GDF3-05890-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KCNMB4/GDF3-05890-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KCNMB4/GDF3-05890-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KCNMB4/GDF3-05890-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KCNMB4/GDF3-05890-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KCNMB4/GDF3-05890-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KCNMB4/GDF3-05890-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KCNMB4/GDF3-05890-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KCNMB4/GDF3-05890-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KCNMB4/GDF3-05890-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KCNMB4/GDF3-05890-AQAQ |
467nm;467nm |
418nm;418nm |
|
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