KCNAB2-POLB Gene Fusion FISH Probe
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Catalog: |
GFFP-KCNAB2/POLB-05907 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The KCNAB2-POLB Gene Fusion FISH Probecan detect the fusion of KCNAB2 and POLB genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
KCNAB2-POLB Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
DNA Polymerase Beta |
Gene Summary 1 |
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011] |
Chromosome 1 |
Chromosome 8 |
Locus 1 |
8p11.21 |
Coordinates 1 |
This gene maps to 42195972-42229331 in GRCh37 coordinates. |
Gene Name 2 |
Potassium Voltage-gated Channel Subfamily A Regulatory Beta Subunit 2 |
Gene Summary 2 |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1p36.31 |
Coordinates 2 |
This gene maps to 6052357-6161253 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-KCNAB2/POLB-05907-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-KCNAB2/POLB-05907-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-KCNAB2/POLB-05907-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-KCNAB2/POLB-05907-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-KCNAB2/POLB-05907-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-KCNAB2/POLB-05907-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-KCNAB2/POLB-05907-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-KCNAB2/POLB-05907-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-KCNAB2/POLB-05907-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-KCNAB2/POLB-05907-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-KCNAB2/POLB-05907-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-KCNAB2/POLB-05907-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-KCNAB2/POLB-05907-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-KCNAB2/POLB-05907-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-KCNAB2/POLB-05907-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-KCNAB2/POLB-05907-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-KCNAB2/POLB-05907-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-KCNAB2/POLB-05907-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-KCNAB2/POLB-05907-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-KCNAB2/POLB-05907-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-KCNAB2/POLB-05907-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-KCNAB2/POLB-05907-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-KCNAB2/POLB-05907-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-KCNAB2/POLB-05907-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-KCNAB2/POLB-05907-AQAQ |
467nm;467nm |
418nm;418nm |
|
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