ISY1-MASP1 Gene Fusion FISH Probe
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Catalog: |
GFFP-ISY1/MASP1-05703 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ISY1-MASP1 Gene Fusion FISH Probecan detect the fusion of ISY1 and MASP1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ISY1-MASP1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Mannan Binding Lectin Serine Peptidase 1 |
Gene Summary 1 |
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3q27.3 |
Coordinates 1 |
This gene maps to 186933872-187009810 in GRCh37 coordinates. |
Gene Name 2 |
ISY1 Splicing Factor Homolog |
Gene Summary 2 |
The ISY1 Splicing Factor Homolog (ISY1) gene is located on chr3 :128846258-128880073 at 3q21.3. |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3q21.3 |
Coordinates 2 |
This gene maps to 128846258-128880073 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ISY1/MASP1-05703-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ISY1/MASP1-05703-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ISY1/MASP1-05703-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ISY1/MASP1-05703-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ISY1/MASP1-05703-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ISY1/MASP1-05703-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ISY1/MASP1-05703-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ISY1/MASP1-05703-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ISY1/MASP1-05703-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ISY1/MASP1-05703-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ISY1/MASP1-05703-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ISY1/MASP1-05703-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ISY1/MASP1-05703-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ISY1/MASP1-05703-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ISY1/MASP1-05703-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ISY1/MASP1-05703-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ISY1/MASP1-05703-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ISY1/MASP1-05703-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ISY1/MASP1-05703-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ISY1/MASP1-05703-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ISY1/MASP1-05703-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ISY1/MASP1-05703-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ISY1/MASP1-05703-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ISY1/MASP1-05703-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ISY1/MASP1-05703-AQAQ |
467nm;467nm |
418nm;418nm |
|
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