IPO11-CENPJ Gene Fusion FISH Probe
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Catalog: |
GFFP-IPO11/CENPJ-05752 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The IPO11-CENPJ Gene Fusion FISH Probecan detect the fusion of IPO11 and CENPJ genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
IPO11-CENPJ Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Importin 11 |
Gene Summary 1 |
Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied by OMIM, Sep 2008] |
Chromosome 1 |
Chromosome 5 |
Locus 1 |
5q12.1 |
Coordinates 1 |
This gene maps to 61708572-61924416 in GRCh37 coordinates. |
Gene Name 2 |
Centromere Protein J |
Gene Summary 2 |
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012] |
Chromosome 2 |
Chromosome13 |
Locus 2 |
13q12.12-q12.13 |
Coordinates 2 |
This gene maps to 25456411-25497085 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-IPO11/CENPJ-05752-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-IPO11/CENPJ-05752-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-IPO11/CENPJ-05752-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-IPO11/CENPJ-05752-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-IPO11/CENPJ-05752-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-IPO11/CENPJ-05752-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-IPO11/CENPJ-05752-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-IPO11/CENPJ-05752-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-IPO11/CENPJ-05752-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-IPO11/CENPJ-05752-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-IPO11/CENPJ-05752-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-IPO11/CENPJ-05752-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-IPO11/CENPJ-05752-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-IPO11/CENPJ-05752-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-IPO11/CENPJ-05752-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-IPO11/CENPJ-05752-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-IPO11/CENPJ-05752-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-IPO11/CENPJ-05752-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-IPO11/CENPJ-05752-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-IPO11/CENPJ-05752-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-IPO11/CENPJ-05752-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-IPO11/CENPJ-05752-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-IPO11/CENPJ-05752-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-IPO11/CENPJ-05752-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-IPO11/CENPJ-05752-AQAQ |
467nm;467nm |
418nm;418nm |
|
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