INSIG1-DPP6 Gene Fusion FISH Probe
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Catalog: |
GFFP-INSIG1/DPP6-05774 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The INSIG1-DPP6 Gene Fusion FISH Probecan detect the fusion of INSIG1 and DPP6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
INSIG1-DPP6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Dipeptidyl Peptidase Like 6 |
Gene Summary 1 |
This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
Chromosome 1 |
Chromosome 7 |
Locus 1 |
7q36.2 |
Coordinates 1 |
This gene maps to 153584418-154685995 in GRCh37 coordinates. |
Gene Name 2 |
Insulin Induced Gene 1 |
Gene Summary 2 |
This gene encodes an endoplasmic reticulum membrane protein that regulates cholesterol metabolism, lipogenesis, and glucose homeostasis. The encoded protein has six transmembrane helices which contain an effector protein binding site. It binds the sterol-sensing domains of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), and is essential for the sterol-mediated trafficking of these two proteins. It promotes the endoplasmic reticulum retention of SCAP and the ubiquitin-mediated degradation of HMG-CoA reductase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
Chromosome 2 |
Chromosome7 |
Locus 2 |
7q36.3 |
Coordinates 2 |
This gene maps to 155089485-155101945 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-INSIG1/DPP6-05774-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-INSIG1/DPP6-05774-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-INSIG1/DPP6-05774-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-INSIG1/DPP6-05774-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-INSIG1/DPP6-05774-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-INSIG1/DPP6-05774-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-INSIG1/DPP6-05774-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-INSIG1/DPP6-05774-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-INSIG1/DPP6-05774-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-INSIG1/DPP6-05774-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-INSIG1/DPP6-05774-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-INSIG1/DPP6-05774-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-INSIG1/DPP6-05774-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-INSIG1/DPP6-05774-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-INSIG1/DPP6-05774-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-INSIG1/DPP6-05774-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-INSIG1/DPP6-05774-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-INSIG1/DPP6-05774-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-INSIG1/DPP6-05774-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-INSIG1/DPP6-05774-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-INSIG1/DPP6-05774-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-INSIG1/DPP6-05774-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-INSIG1/DPP6-05774-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-INSIG1/DPP6-05774-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-INSIG1/DPP6-05774-AQAQ |
467nm;467nm |
418nm;418nm |
|
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