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INCENP-CCS Gene Fusion FISH Probe

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Catalog: GFFP-INCENP/CCS-05791
Classification: Gene Fusion FISH Probes
Description: The INCENP-CCS Gene Fusion FISH Probecan detect the fusion of INCENP and CCS genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: INCENP-CCS Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Inner Centromere Protein
Gene Summary 1 In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).[supplied by OMIM, Mar 2008]
Chromosome 1 Chromosome 11
Locus 1 11q12.3
Coordinates 1 This gene maps to 61891444-61920635 in GRCh37 coordinates.
Gene Name 2 Copper Chaperone For Superoxide Dismutase
Gene Summary 2 Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome11
Locus 2 11q13.2
Coordinates 2 This gene maps to 66360689-66373490 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-INCENP/CCS-05791-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-INCENP/CCS-05791-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-INCENP/CCS-05791-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-INCENP/CCS-05791-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-INCENP/CCS-05791-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-INCENP/CCS-05791-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-INCENP/CCS-05791-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-INCENP/CCS-05791-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-INCENP/CCS-05791-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-INCENP/CCS-05791-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-INCENP/CCS-05791-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-INCENP/CCS-05791-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-INCENP/CCS-05791-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-INCENP/CCS-05791-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-INCENP/CCS-05791-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-INCENP/CCS-05791-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-INCENP/CCS-05791-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-INCENP/CCS-05791-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-INCENP/CCS-05791-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-INCENP/CCS-05791-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-INCENP/CCS-05791-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-INCENP/CCS-05791-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-INCENP/CCS-05791-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-INCENP/CCS-05791-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-INCENP/CCS-05791-AQAQ 467nm;467nm 418nm;418nm

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