ILF3-PDE4A Gene Fusion FISH Probe
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Catalog: |
GFFP-ILF3/PDE4A-05804 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ILF3-PDE4A Gene Fusion FISH Probecan detect the fusion of ILF3 and PDE4A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ILF3-PDE4A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Interleukin Enhancer Binding Factor 3 |
Gene Summary 1 |
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.2 |
Coordinates 1 |
This gene maps to 10764936-10803095 in GRCh37 coordinates. |
Gene Name 2 |
Phosphodiesterase 4A |
Gene Summary 2 |
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.2 |
Coordinates 2 |
This gene maps to 10527448-10580307 in GRCh37 coordinates. |
Associated Diseases |
Stomach Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ILF3/PDE4A-05804-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ILF3/PDE4A-05804-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ILF3/PDE4A-05804-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ILF3/PDE4A-05804-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ILF3/PDE4A-05804-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ILF3/PDE4A-05804-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ILF3/PDE4A-05804-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ILF3/PDE4A-05804-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ILF3/PDE4A-05804-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ILF3/PDE4A-05804-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ILF3/PDE4A-05804-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ILF3/PDE4A-05804-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ILF3/PDE4A-05804-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ILF3/PDE4A-05804-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ILF3/PDE4A-05804-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ILF3/PDE4A-05804-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ILF3/PDE4A-05804-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ILF3/PDE4A-05804-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ILF3/PDE4A-05804-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ILF3/PDE4A-05804-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ILF3/PDE4A-05804-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ILF3/PDE4A-05804-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ILF3/PDE4A-05804-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ILF3/PDE4A-05804-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ILF3/PDE4A-05804-AQAQ |
467nm;467nm |
418nm;418nm |
|
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