IL17RA-SCARF2 Gene Fusion FISH Probe
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Catalog: |
GFFP-IL17RA/SCARF2-05827 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The IL17RA-SCARF2 Gene Fusion FISH Probecan detect the fusion of IL17RA and SCARF2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
IL17RA-SCARF2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Interleukin 17 Receptor A |
Gene Summary 1 |
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014] |
Chromosome 1 |
Chromosome 22 |
Locus 1 |
22q11.1 |
Coordinates 1 |
This gene maps to 17565850-17596584 in GRCh37 coordinates. |
Gene Name 2 |
Scavenger Receptor Class F Member 2 |
Gene Summary 2 |
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome22 |
Locus 2 |
22q11.21 |
Coordinates 2 |
This gene maps to 20778873-20792146 in GRCh37 coordinates. |
Associated Diseases |
Lung Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-IL17RA/SCARF2-05827-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-IL17RA/SCARF2-05827-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-IL17RA/SCARF2-05827-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-IL17RA/SCARF2-05827-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-IL17RA/SCARF2-05827-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-IL17RA/SCARF2-05827-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-IL17RA/SCARF2-05827-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-IL17RA/SCARF2-05827-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-IL17RA/SCARF2-05827-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-IL17RA/SCARF2-05827-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-IL17RA/SCARF2-05827-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-IL17RA/SCARF2-05827-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-IL17RA/SCARF2-05827-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-IL17RA/SCARF2-05827-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-IL17RA/SCARF2-05827-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-IL17RA/SCARF2-05827-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-IL17RA/SCARF2-05827-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-IL17RA/SCARF2-05827-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-IL17RA/SCARF2-05827-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-IL17RA/SCARF2-05827-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-IL17RA/SCARF2-05827-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-IL17RA/SCARF2-05827-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-IL17RA/SCARF2-05827-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-IL17RA/SCARF2-05827-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-IL17RA/SCARF2-05827-AQAQ |
467nm;467nm |
418nm;418nm |
|
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