IGF1R-RAB27A Gene Fusion FISH Probe
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Catalog: |
GFFP-IGF1R/RAB27A-05575 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The IGF1R-RAB27A Gene Fusion FISH Probecan detect the fusion of IGF1R and RAB27A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
IGF1R-RAB27A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Insulin Like Growth Factor 1 Receptor |
Gene Summary 1 |
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Chromosome 1 |
Chromosome 15 |
Locus 1 |
15q26.3 |
Coordinates 1 |
This gene maps to 99192760-99507759 in GRCh37 coordinates. |
Gene Name 2 |
RAB27A, Member RAS Oncogene Family |
Gene Summary 2 |
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q21.3 |
Coordinates 2 |
This gene maps to 55495163-55582013 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-IGF1R/RAB27A-05575-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-IGF1R/RAB27A-05575-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-IGF1R/RAB27A-05575-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-IGF1R/RAB27A-05575-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-IGF1R/RAB27A-05575-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-IGF1R/RAB27A-05575-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-IGF1R/RAB27A-05575-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-IGF1R/RAB27A-05575-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-IGF1R/RAB27A-05575-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-IGF1R/RAB27A-05575-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-IGF1R/RAB27A-05575-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-IGF1R/RAB27A-05575-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-IGF1R/RAB27A-05575-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-IGF1R/RAB27A-05575-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-IGF1R/RAB27A-05575-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-IGF1R/RAB27A-05575-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-IGF1R/RAB27A-05575-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-IGF1R/RAB27A-05575-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-IGF1R/RAB27A-05575-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-IGF1R/RAB27A-05575-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-IGF1R/RAB27A-05575-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-IGF1R/RAB27A-05575-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-IGF1R/RAB27A-05575-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-IGF1R/RAB27A-05575-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-IGF1R/RAB27A-05575-AQAQ |
467nm;467nm |
418nm;418nm |
|
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