ICAM3-TYK2 Gene Fusion FISH Probe
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Catalog: |
GFFP-ICAM3/TYK2-05608 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ICAM3-TYK2 Gene Fusion FISH Probecan detect the fusion of ICAM3 and TYK2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ICAM3-TYK2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Intercellular Adhesion Molecule 3 |
Gene Summary 1 |
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] |
Chromosome 1 |
Chromosome 19 |
Locus 1 |
19p13.2 |
Coordinates 1 |
This gene maps to 10444451-10450345 in GRCh37 coordinates. |
Gene Name 2 |
Tyrosine Kinase 2 |
Gene Summary 2 |
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.2 |
Coordinates 2 |
This gene maps to 10461203-10491248 in GRCh37 coordinates. |
Associated Diseases |
Pancreatic Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ICAM3/TYK2-05608-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ICAM3/TYK2-05608-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ICAM3/TYK2-05608-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ICAM3/TYK2-05608-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ICAM3/TYK2-05608-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ICAM3/TYK2-05608-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ICAM3/TYK2-05608-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ICAM3/TYK2-05608-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ICAM3/TYK2-05608-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ICAM3/TYK2-05608-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ICAM3/TYK2-05608-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ICAM3/TYK2-05608-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ICAM3/TYK2-05608-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ICAM3/TYK2-05608-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ICAM3/TYK2-05608-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ICAM3/TYK2-05608-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ICAM3/TYK2-05608-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ICAM3/TYK2-05608-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ICAM3/TYK2-05608-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ICAM3/TYK2-05608-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ICAM3/TYK2-05608-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ICAM3/TYK2-05608-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ICAM3/TYK2-05608-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ICAM3/TYK2-05608-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ICAM3/TYK2-05608-AQAQ |
467nm;467nm |
418nm;418nm |
|
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