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HTRA1-C7 Gene Fusion FISH Probe

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Catalog: GFFP-HTRA1/C7-05544
Classification: Gene Fusion FISH Probes
Description: The HTRA1-C7 Gene Fusion FISH Probecan detect the fusion of HTRA1 and C7 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: HTRA1-C7 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Complement C7
Gene Summary 1 This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016]
Chromosome 1 Chromosome 5
Locus 1 5p13.1
Coordinates 1 This gene maps to 40909598-40983042 in GRCh37 coordinates.
Gene Name 2 HtrA Serine Peptidase 1
Gene Summary 2 This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome10
Locus 2 10q26.13
Coordinates 2 This gene maps to 124221040-124274424 in GRCh37 coordinates.
Associated Diseases Kidney Renal Papillary Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-HTRA1/C7-05544-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-HTRA1/C7-05544-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-HTRA1/C7-05544-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-HTRA1/C7-05544-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-HTRA1/C7-05544-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-HTRA1/C7-05544-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-HTRA1/C7-05544-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-HTRA1/C7-05544-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-HTRA1/C7-05544-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-HTRA1/C7-05544-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-HTRA1/C7-05544-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-HTRA1/C7-05544-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-HTRA1/C7-05544-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-HTRA1/C7-05544-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-HTRA1/C7-05544-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-HTRA1/C7-05544-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-HTRA1/C7-05544-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-HTRA1/C7-05544-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-HTRA1/C7-05544-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-HTRA1/C7-05544-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-HTRA1/C7-05544-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-HTRA1/C7-05544-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-HTRA1/C7-05544-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-HTRA1/C7-05544-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-HTRA1/C7-05544-AQAQ 467nm;467nm 418nm;418nm

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