HLA-DRA-SNW1 Gene Fusion FISH Probe
Add to Cart
Catalog: |
GFFP-HLA/DRA/SNW1-05447 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The HLA-DRA-SNW1 Gene Fusion FISH Probecan detect the fusion of HLA-DRA and SNW1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
HLA-DRA-SNW1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Major Histocompatibility Complex, Class II, DR Alpha |
Gene Summary 1 |
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 6_mann_hap4 |
Locus 1 |
6p21.32 |
Coordinates 1 |
This gene maps to 3749678-3754894 in GRCh37 coordinates. |
Gene Name 2 |
SNW Domain Containing 1 |
Gene Summary 2 |
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Chromosome 2 |
Chromosome14 |
Locus 2 |
14q24.3 |
Coordinates 2 |
This gene maps to 78183943-78227497 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-HLA/DRA/SNW1-05447-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-HLA/DRA/SNW1-05447-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-HLA/DRA/SNW1-05447-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-HLA/DRA/SNW1-05447-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-HLA/DRA/SNW1-05447-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-HLA/DRA/SNW1-05447-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-HLA/DRA/SNW1-05447-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-HLA/DRA/SNW1-05447-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-HLA/DRA/SNW1-05447-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-HLA/DRA/SNW1-05447-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-HLA/DRA/SNW1-05447-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-HLA/DRA/SNW1-05447-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-HLA/DRA/SNW1-05447-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-HLA/DRA/SNW1-05447-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-HLA/DRA/SNW1-05447-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-HLA/DRA/SNW1-05447-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-HLA/DRA/SNW1-05447-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-HLA/DRA/SNW1-05447-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-HLA/DRA/SNW1-05447-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-HLA/DRA/SNW1-05447-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-HLA/DRA/SNW1-05447-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-HLA/DRA/SNW1-05447-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-HLA/DRA/SNW1-05447-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-HLA/DRA/SNW1-05447-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-HLA/DRA/SNW1-05447-AQAQ |
467nm;467nm |
418nm;418nm |
|
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