HDAC5-MYO18A Gene Fusion FISH Probe
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Catalog: |
GFFP-HDAC5/MYO18A-05271 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The HDAC5-MYO18A Gene Fusion FISH Probecan detect the fusion of HDAC5 and MYO18A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
HDAC5-MYO18A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Histone Deacetylase 5 |
Gene Summary 1 |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 17 |
Locus 1 |
17q21.31 |
Coordinates 1 |
This gene maps to 42154120-42201014 in GRCh37 coordinates. |
Gene Name 2 |
Myosin XVIIIA |
Gene Summary 2 |
The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016] |
Chromosome 2 |
Chromosome17 |
Locus 2 |
17q11.2 |
Coordinates 2 |
This gene maps to 27400527-27507407 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-HDAC5/MYO18A-05271-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-HDAC5/MYO18A-05271-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-HDAC5/MYO18A-05271-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-HDAC5/MYO18A-05271-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-HDAC5/MYO18A-05271-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-HDAC5/MYO18A-05271-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-HDAC5/MYO18A-05271-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-HDAC5/MYO18A-05271-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-HDAC5/MYO18A-05271-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-HDAC5/MYO18A-05271-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-HDAC5/MYO18A-05271-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-HDAC5/MYO18A-05271-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-HDAC5/MYO18A-05271-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-HDAC5/MYO18A-05271-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-HDAC5/MYO18A-05271-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-HDAC5/MYO18A-05271-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-HDAC5/MYO18A-05271-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-HDAC5/MYO18A-05271-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-HDAC5/MYO18A-05271-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-HDAC5/MYO18A-05271-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-HDAC5/MYO18A-05271-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-HDAC5/MYO18A-05271-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-HDAC5/MYO18A-05271-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-HDAC5/MYO18A-05271-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-HDAC5/MYO18A-05271-AQAQ |
467nm;467nm |
418nm;418nm |
|
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