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H2AFY-CNOT6 Gene Fusion FISH Probe

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Catalog: GFFP-H2AFY/CNOT6-15168
Classification: Gene Fusion FISH Probes
Description: The H2AFY-CNOT6 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: H2AFY-CNOT6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 H2A Histone Family Member Y
Gene Summary 1 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
Chromosome 1 Chromosome 5
Locus 1 5q31.1
Coordinates 1 This gene maps to 134670070-134735577in GRCh37 coordinates.
Gene Name 2 CCR4-NOT Transcription Complex Subunit 6
Gene Summary 2 This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014]
Chromosome 2 Chromosome5
Locus 2 5q35.3
Coordinates 2 This gene maps to 179921416-180005353 in GRCh37 coordinates.
Associated Diseases Breast Invasive Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-H2AFY/CNOT6-15168-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-H2AFY/CNOT6-15168-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-H2AFY/CNOT6-15168-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-H2AFY/CNOT6-15168-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-H2AFY/CNOT6-15168-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-H2AFY/CNOT6-15168-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-H2AFY/CNOT6-15168-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-H2AFY/CNOT6-15168-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-H2AFY/CNOT6-15168-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-H2AFY/CNOT6-15168-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-H2AFY/CNOT6-15168-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-H2AFY/CNOT6-15168-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-H2AFY/CNOT6-15168-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-H2AFY/CNOT6-15168-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-H2AFY/CNOT6-15168-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-H2AFY/CNOT6-15168-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-H2AFY/CNOT6-15168-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-H2AFY/CNOT6-15168-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-H2AFY/CNOT6-15168-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-H2AFY/CNOT6-15168-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-H2AFY/CNOT6-15168-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-H2AFY/CNOT6-15168-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-H2AFY/CNOT6-15168-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-H2AFY/CNOT6-15168-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-H2AFY/CNOT6-15168-AQAQ 467nm;467nm 418nm;418nm

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