CIITA-PRDM16 Gene Fusion FISH Probe
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Catalog: |
GFFP-CIITA/PRDM16-02462 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The CIITA-PRDM16 Gene Fusion FISH Probecan detect the fusion of CIITA and PRDM16 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
CIITA-PRDM16 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Class II Major Histocompatibility Complex Transactivator |
Gene Summary 1 |
This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the "master control factor" for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
Chromosome 1 |
Chromosome 16 |
Locus 1 |
16p13.13 |
Coordinates 1 |
This gene maps to 10971054-11018840 in GRCh37 coordinates. |
Gene Name 2 |
PR/SET Domain 16 |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1p36.32 |
Coordinates 2 |
This gene maps to 2985741-3355185 in GRCh37 coordinates. |
Associated Diseases |
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-CIITA/PRDM16-02462-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-CIITA/PRDM16-02462-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-CIITA/PRDM16-02462-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-CIITA/PRDM16-02462-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-CIITA/PRDM16-02462-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-CIITA/PRDM16-02462-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-CIITA/PRDM16-02462-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-CIITA/PRDM16-02462-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-CIITA/PRDM16-02462-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-CIITA/PRDM16-02462-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-CIITA/PRDM16-02462-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-CIITA/PRDM16-02462-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-CIITA/PRDM16-02462-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-CIITA/PRDM16-02462-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-CIITA/PRDM16-02462-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-CIITA/PRDM16-02462-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-CIITA/PRDM16-02462-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-CIITA/PRDM16-02462-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-CIITA/PRDM16-02462-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-CIITA/PRDM16-02462-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-CIITA/PRDM16-02462-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-CIITA/PRDM16-02462-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-CIITA/PRDM16-02462-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-CIITA/PRDM16-02462-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-CIITA/PRDM16-02462-AQAQ |
467nm;467nm |
418nm;418nm |
|
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