CD59-FBXO3 Gene Fusion FISH Probe
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Catalog: |
GFFP-CD59/FBXO3-02115 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The CD59-FBXO3 Gene Fusion FISH Probecan detect the fusion of CD59 and FBXO3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
CD59-FBXO3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
CD59 Molecule (CD59 Blood Group) |
Gene Summary 1 |
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11p13 |
Coordinates 1 |
This gene maps to 33724555-33758025 in GRCh37 coordinates. |
Gene Name 2 |
F-box Protein 3 |
Chromosome 2 |
Chromosome11 |
Locus 2 |
11p13 |
Coordinates 2 |
This gene maps to 33762489-33796071 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-CD59/FBXO3-02115-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-CD59/FBXO3-02115-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-CD59/FBXO3-02115-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-CD59/FBXO3-02115-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-CD59/FBXO3-02115-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-CD59/FBXO3-02115-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-CD59/FBXO3-02115-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-CD59/FBXO3-02115-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-CD59/FBXO3-02115-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-CD59/FBXO3-02115-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-CD59/FBXO3-02115-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-CD59/FBXO3-02115-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-CD59/FBXO3-02115-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-CD59/FBXO3-02115-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-CD59/FBXO3-02115-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-CD59/FBXO3-02115-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-CD59/FBXO3-02115-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-CD59/FBXO3-02115-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-CD59/FBXO3-02115-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-CD59/FBXO3-02115-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-CD59/FBXO3-02115-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-CD59/FBXO3-02115-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-CD59/FBXO3-02115-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-CD59/FBXO3-02115-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-CD59/FBXO3-02115-AQAQ |
467nm;467nm |
418nm;418nm |
|
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