BCR-UPB1 Gene Fusion FISH Probe
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Catalog: |
GFFP-BCR/UPB1-13893 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The BCR-UPB1 Gene Fusion FISH Probecan detect the fusion of BCR and UPB1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
BCR-UPB1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
BCR, RhoGEF And GTPase Activating Protein |
Gene Summary 1 |
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 22 |
Locus 1 |
22q11.23 |
Coordinates 1 |
This gene maps to 23522551-23660224 in GRCh37 coordinates. |
Gene Name 2 |
Beta-ureidopropionase 1 |
Chromosome 2 |
Chromosome22 |
Locus 2 |
22q11.23 |
Coordinates 2 |
This gene maps to 24891250-24922553 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-BCR/UPB1-13893-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-BCR/UPB1-13893-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-BCR/UPB1-13893-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-BCR/UPB1-13893-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-BCR/UPB1-13893-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-BCR/UPB1-13893-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-BCR/UPB1-13893-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-BCR/UPB1-13893-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-BCR/UPB1-13893-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-BCR/UPB1-13893-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-BCR/UPB1-13893-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-BCR/UPB1-13893-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-BCR/UPB1-13893-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-BCR/UPB1-13893-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-BCR/UPB1-13893-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-BCR/UPB1-13893-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-BCR/UPB1-13893-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-BCR/UPB1-13893-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-BCR/UPB1-13893-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-BCR/UPB1-13893-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-BCR/UPB1-13893-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-BCR/UPB1-13893-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-BCR/UPB1-13893-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-BCR/UPB1-13893-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-BCR/UPB1-13893-AQAQ |
467nm;467nm |
418nm;418nm |
|
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