AXIN1-BBX Gene Fusion FISH Probe
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Catalog: |
GFFP-AXIN1/BBX-01430 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The AXIN1-BBX Gene Fusion FISH Probecan detect the fusion of AXIN1 and BBX genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
AXIN1-BBX Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Axin 1 |
Gene Summary 1 |
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Chromosome 1 |
Chromosome 16 |
Locus 1 |
16p13.3 |
Coordinates 1 |
This gene maps to 337439-402676 in GRCh37 coordinates. |
Gene Name 2 |
BBX, HMG-box Containing |
Chromosome 2 |
Chromosome3 |
Locus 2 |
3q13.12 |
Coordinates 2 |
This gene maps to 107241782-107530049 in GRCh37 coordinates. |
Associated Diseases |
Ovarian Serous Cystadenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-AXIN1/BBX-01430-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-AXIN1/BBX-01430-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-AXIN1/BBX-01430-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-AXIN1/BBX-01430-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-AXIN1/BBX-01430-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-AXIN1/BBX-01430-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-AXIN1/BBX-01430-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-AXIN1/BBX-01430-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-AXIN1/BBX-01430-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-AXIN1/BBX-01430-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-AXIN1/BBX-01430-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-AXIN1/BBX-01430-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-AXIN1/BBX-01430-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-AXIN1/BBX-01430-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-AXIN1/BBX-01430-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-AXIN1/BBX-01430-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-AXIN1/BBX-01430-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-AXIN1/BBX-01430-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-AXIN1/BBX-01430-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-AXIN1/BBX-01430-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-AXIN1/BBX-01430-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-AXIN1/BBX-01430-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-AXIN1/BBX-01430-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-AXIN1/BBX-01430-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-AXIN1/BBX-01430-AQAQ |
467nm;467nm |
418nm;418nm |
|
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