APP-CCT8 Gene Fusion FISH Probe
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Catalog: |
GFFP-APP/CCT8-00670 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The APP-CCT8 Gene Fusion FISH Probecan detect the fusion of APP and CCT8 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
APP-CCT8 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Amyloid Beta Precursor Protein |
Gene Summary 1 |
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014] |
Chromosome 1 |
Chromosome 21 |
Locus 1 |
21q21.3 |
Coordinates 1 |
This gene maps to 27252860-27543446 in GRCh37 coordinates. |
Gene Name 2 |
Chaperonin Containing TCP1 Subunit 8 |
Gene Summary 2 |
This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013] |
Chromosome 2 |
Chromosome21 |
Locus 2 |
21q21.3 |
Coordinates 2 |
This gene maps to 30428647-30446010 in GRCh37 coordinates. |
Associated Diseases |
Skin Cutaneous Melanoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-APP/CCT8-00670-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-APP/CCT8-00670-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-APP/CCT8-00670-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-APP/CCT8-00670-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-APP/CCT8-00670-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-APP/CCT8-00670-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-APP/CCT8-00670-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-APP/CCT8-00670-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-APP/CCT8-00670-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-APP/CCT8-00670-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-APP/CCT8-00670-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-APP/CCT8-00670-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-APP/CCT8-00670-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-APP/CCT8-00670-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-APP/CCT8-00670-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-APP/CCT8-00670-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-APP/CCT8-00670-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-APP/CCT8-00670-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-APP/CCT8-00670-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-APP/CCT8-00670-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-APP/CCT8-00670-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-APP/CCT8-00670-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-APP/CCT8-00670-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-APP/CCT8-00670-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-APP/CCT8-00670-AQAQ |
467nm;467nm |
418nm;418nm |
|
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