APLP2-C7 Gene Fusion FISH Probe
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| Catalog: |
GFFP-APLP2/C7-14827 |
| Classification: |
Gene Fusion FISH Probes |
| Description: |
The APLP2-C7 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Category: |
Gene Fusion FISH Probes |
| Application: |
APLP2-C7 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name 1 |
Amyloid Beta Precursor Like Protein 2 |
| Gene Summary 1 |
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
| Chromosome 1 |
Chromosome 11 |
| Locus 1 |
11q24.3 |
| Coordinates 1 |
This gene maps to 129939715-130014706in GRCh37 coordinates. |
| Gene Name 2 |
Complement C7 |
| Gene Summary 2 |
This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016] |
| Chromosome 2 |
Chromosome5 |
| Locus 2 |
5p13.1 |
| Coordinates 2 |
This gene maps to 40909598-40983042 in GRCh37 coordinates. |
| Associated Diseases |
Thyroid Carcinoma; Kidney Chromophobe |
| Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
RE; RE
|
GFFP-APLP2/C7-14827-RERE |
599nm;599nm |
580nm;580nm |
|
| 2 |
RE; OR
|
GFFP-APLP2/C7-14827-REOR |
599nm;573nm |
580nm;548nm |
|
| 3 |
RE; GO
|
GFFP-APLP2/C7-14827-REGO |
599nm;551nm |
580nm;525nm |
|
| 4 |
RE; GR
|
GFFP-APLP2/C7-14827-REGR |
599nm;515nm |
580nm;491nm |
|
| 5 |
RE; AQ
|
GFFP-APLP2/C7-14827-REAQ |
599nm;467nm |
580nm;418nm |
|
| 6 |
OR; RE
|
GFFP-APLP2/C7-14827-ORRE |
573nm;599nm |
548nm;580nm |
|
| 7 |
OR; OR
|
GFFP-APLP2/C7-14827-OROR |
573nm;573nm |
548nm;548nm |
|
| 8 |
OR; GO
|
GFFP-APLP2/C7-14827-ORGO |
573nm;551nm |
548nm;525nm |
|
| 9 |
OR; GR
|
GFFP-APLP2/C7-14827-ORGR |
573nm;515nm |
548nm;491nm |
|
| 10 |
OR; AQ
|
GFFP-APLP2/C7-14827-ORAQ |
573nm;467nm |
548nm;418nm |
|
| 11 |
GO; RE
|
GFFP-APLP2/C7-14827-GORE |
551nm;599nm |
525nm;580nm |
|
| 12 |
GO; OR
|
GFFP-APLP2/C7-14827-GOOR |
551nm;573nm |
525nm;548nm |
|
| 13 |
GO; GO
|
GFFP-APLP2/C7-14827-GOGO |
551nm;551nm |
525nm;525nm |
|
| 14 |
GO; GR
|
GFFP-APLP2/C7-14827-GOGR |
551nm;515nm |
525nm;491nm |
|
| 15 |
GO; AQ
|
GFFP-APLP2/C7-14827-GOAQ |
551nm;467nm |
525nm;418nm |
|
| 16 |
GR; RE
|
GFFP-APLP2/C7-14827-GRRE |
515nm;599nm |
491nm;580nm |
|
| 17 |
GR; OR
|
GFFP-APLP2/C7-14827-GROR |
515nm;573nm |
491nm;548nm |
|
| 18 |
GR; GO
|
GFFP-APLP2/C7-14827-GRGO |
515nm;551nm |
491nm;525nm |
|
| 19 |
GR; GR
|
GFFP-APLP2/C7-14827-GRGR |
515nm;515nm |
491nm;491nm |
|
| 20 |
GR; AQ
|
GFFP-APLP2/C7-14827-GRAQ |
515nm;467nm |
491nm;418nm |
|
| 21 |
AQ; RE
|
GFFP-APLP2/C7-14827-AQRE |
467nm;599nm |
418nm;580nm |
|
| 22 |
AQ; OR
|
GFFP-APLP2/C7-14827-AQOR |
467nm;573nm |
418nm;548nm |
|
| 23 |
AQ; GO
|
GFFP-APLP2/C7-14827-AQGO |
467nm;551nm |
418nm;525nm |
|
| 24 |
AQ; GR
|
GFFP-APLP2/C7-14827-AQGR |
467nm;515nm |
418nm;491nm |
|
| 25 |
AQ; AQ
|
GFFP-APLP2/C7-14827-AQAQ |
467nm;467nm |
418nm;418nm |
|
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