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ANKRD12-PTPRM Gene Fusion FISH Probe

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Catalog: GFFP-ANKRD12/PTPRM-00453
Classification: Gene Fusion FISH Probes
Description: The ANKRD12-PTPRM Gene Fusion FISH Probecan detect the fusion of ANKRD12 and PTPRM genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ANKRD12-PTPRM Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Protein Tyrosine Phosphatase, Receptor Type M
Gene Summary 1 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Chromosome 1 Chromosome 18
Locus 1 18p11.23
Coordinates 1 This gene maps to 7567313-8406859 in GRCh37 coordinates.
Gene Name 2 Ankyrin Repeat Domain 12
Gene Summary 2 This gene encodes a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Chromosome 2 Chromosome18
Locus 2 18p11.22
Coordinates 2 This gene maps to 9136750-9285983 in GRCh37 coordinates.
Associated Diseases Lung Adenocarcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ANKRD12/PTPRM-00453-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ANKRD12/PTPRM-00453-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ANKRD12/PTPRM-00453-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ANKRD12/PTPRM-00453-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ANKRD12/PTPRM-00453-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ANKRD12/PTPRM-00453-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ANKRD12/PTPRM-00453-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ANKRD12/PTPRM-00453-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ANKRD12/PTPRM-00453-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ANKRD12/PTPRM-00453-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ANKRD12/PTPRM-00453-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ANKRD12/PTPRM-00453-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ANKRD12/PTPRM-00453-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ANKRD12/PTPRM-00453-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ANKRD12/PTPRM-00453-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ANKRD12/PTPRM-00453-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ANKRD12/PTPRM-00453-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ANKRD12/PTPRM-00453-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ANKRD12/PTPRM-00453-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ANKRD12/PTPRM-00453-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ANKRD12/PTPRM-00453-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ANKRD12/PTPRM-00453-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ANKRD12/PTPRM-00453-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ANKRD12/PTPRM-00453-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ANKRD12/PTPRM-00453-AQAQ 467nm;467nm 418nm;418nm

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