ANKH-MXD3 Gene Fusion FISH Probe
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Catalog: |
GFFP-ANKH/MXD3-00489 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ANKH-MXD3 Gene Fusion FISH Probecan detect the fusion of ANKH and MXD3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ANKH-MXD3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
ANKH Inorganic Pyrophosphate Transport Regulator |
Gene Summary 1 |
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 5 |
Locus 1 |
5p15.2 |
Coordinates 1 |
This gene maps to 14704908-14871887 in GRCh37 coordinates. |
Gene Name 2 |
MAX Dimerization Protein 3 |
Gene Summary 2 |
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008] |
Chromosome 2 |
Chromosome5 |
Locus 2 |
5q35.3 |
Coordinates 2 |
This gene maps to 176732500-176739292 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ANKH/MXD3-00489-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ANKH/MXD3-00489-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ANKH/MXD3-00489-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ANKH/MXD3-00489-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ANKH/MXD3-00489-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ANKH/MXD3-00489-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ANKH/MXD3-00489-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ANKH/MXD3-00489-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ANKH/MXD3-00489-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ANKH/MXD3-00489-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ANKH/MXD3-00489-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ANKH/MXD3-00489-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ANKH/MXD3-00489-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ANKH/MXD3-00489-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ANKH/MXD3-00489-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ANKH/MXD3-00489-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ANKH/MXD3-00489-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ANKH/MXD3-00489-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ANKH/MXD3-00489-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ANKH/MXD3-00489-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ANKH/MXD3-00489-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ANKH/MXD3-00489-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ANKH/MXD3-00489-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ANKH/MXD3-00489-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ANKH/MXD3-00489-AQAQ |
467nm;467nm |
418nm;418nm |
|
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