ANK2-ALPK1 Gene Fusion FISH Probe
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Catalog: |
GFFP-ANK2/ALPK1-14815 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ANK2-ALPK1 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ANK2-ALPK1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Ankyrin 2 |
Gene Summary 1 |
This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011] |
Chromosome 1 |
Chromosome 4 |
Locus 1 |
4q25-q26 |
Coordinates 1 |
This gene maps to 113739238-114304896in GRCh37 coordinates. |
Gene Name 2 |
Alpha Kinase 1 |
Gene Summary 2 |
This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
Chromosome 2 |
Chromosome4 |
Locus 2 |
4q25 |
Coordinates 2 |
This gene maps to 113218498-113363764 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma; Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ANK2/ALPK1-14815-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ANK2/ALPK1-14815-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ANK2/ALPK1-14815-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ANK2/ALPK1-14815-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ANK2/ALPK1-14815-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ANK2/ALPK1-14815-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ANK2/ALPK1-14815-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ANK2/ALPK1-14815-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ANK2/ALPK1-14815-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ANK2/ALPK1-14815-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ANK2/ALPK1-14815-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ANK2/ALPK1-14815-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ANK2/ALPK1-14815-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ANK2/ALPK1-14815-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ANK2/ALPK1-14815-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ANK2/ALPK1-14815-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ANK2/ALPK1-14815-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ANK2/ALPK1-14815-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ANK2/ALPK1-14815-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ANK2/ALPK1-14815-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ANK2/ALPK1-14815-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ANK2/ALPK1-14815-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ANK2/ALPK1-14815-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ANK2/ALPK1-14815-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ANK2/ALPK1-14815-AQAQ |
467nm;467nm |
418nm;418nm |
|
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