ANAPC5-KDM2B Gene Fusion FISH Probe
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Catalog: |
GFFP-ANAPC5/KDM2B-14811 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ANAPC5-KDM2B Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ANAPC5-KDM2B Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Anaphase Promoting Complex Subunit 5 |
Gene Summary 1 |
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12q24.31 |
Coordinates 1 |
This gene maps to 121746047-121792012in GRCh37 coordinates. |
Gene Name 2 |
Lysine Demethylase 2B |
Gene Summary 2 |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome12 |
Locus 2 |
12q24.31 |
Coordinates 2 |
This gene maps to 121866899-122018920 in GRCh37 coordinates. |
Associated Diseases |
Stomach Adenocarcinoma; Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ANAPC5/KDM2B-14811-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ANAPC5/KDM2B-14811-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ANAPC5/KDM2B-14811-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ANAPC5/KDM2B-14811-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ANAPC5/KDM2B-14811-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ANAPC5/KDM2B-14811-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ANAPC5/KDM2B-14811-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ANAPC5/KDM2B-14811-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ANAPC5/KDM2B-14811-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ANAPC5/KDM2B-14811-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ANAPC5/KDM2B-14811-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ANAPC5/KDM2B-14811-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ANAPC5/KDM2B-14811-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ANAPC5/KDM2B-14811-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ANAPC5/KDM2B-14811-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ANAPC5/KDM2B-14811-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ANAPC5/KDM2B-14811-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ANAPC5/KDM2B-14811-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ANAPC5/KDM2B-14811-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ANAPC5/KDM2B-14811-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ANAPC5/KDM2B-14811-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ANAPC5/KDM2B-14811-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ANAPC5/KDM2B-14811-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ANAPC5/KDM2B-14811-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ANAPC5/KDM2B-14811-AQAQ |
467nm;467nm |
418nm;418nm |
|
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